Basic Research    

A novel approach for 25-gauge transconjunctival sutureless vitrectomy to evaluate vitreous substitutes in rabbits

Rui-Jin Ran, Ting Wang, Meng-Ying Tao, Yue-Qin Gou, Ming Zhang

The authors provided a practical surgical technique for improving the standard three-port vitrectomy in rabbits in order to establish a proper model for the evaluation of a novel endotamponade substitute. The infusion cannula was firstly placed in the inferior nasal quadrant at 5 o’clock position. The balanced salt solution was continuously fed into the vitreous cavity through the handhold infusion catheter. The vitreous cutter and endoilluminator were then respectively placed in the superior nasal quadrant at 12 o’clock and 2 o’clock positions, using a wide‐angle noncontact viewing system and the Constellation Vision System, and the core vitrectomy was removed. And the surgical procedure via the modified approach does not involve removal of the lens. The modified approach appeared to have few complications, less operation time and better ability to heal the sclera wounds than previous reports. The novel artificial vitreous body could be formed in situ by cross-linking in less than 1min, with good transparency. Fundus photography and SD-OCT showed that the retina breaks were repaired well without retinal detachment. The novel hydrogel might serve as a promising candidate in treating vitreoretinal diseases. The modified surgical approach is worthy of application in establishing animal endotamponade models.

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25G经结膜无缝线玻璃体切除术评估兔玻璃体替代物的新方法

作者提供了一种实用的手术技术改良标准三通道玻璃体切除术，建立一个合适的兔模型用于评估一种新型的内眼填充物替代品。首先将灌注管道置于鼻下象限5点位置，经手持灌注导管将平衡盐溶液连续注入玻璃体腔。玻切头通道和眼内照明通道分别置于鼻上象限12点和2点位置，用非接触广角镜和微创玻璃体切割仪(Constellation Vision System)切除中心玻璃体。通过改良方法进行的手术不需要摘除晶状体。与以前的报道相比，改良的方法并发症少，手术时间短，巩膜伤口愈合快。新型人工玻璃体可以在不到1分钟的时间内通过交联原位形成，具有良好的透明度。眼底照相和SD-OCT显示视网膜裂孔修复良好，无视网膜脱离。这种新型水凝胶有望成为治疗玻璃体视网膜疾病的一种有前景的替代物。改良的手术方法可应用于建立动物眼内填充模型。

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    Clinical Research    

Agreement of intraocular pressure measurement with Corvis ST, non-contact tonometer, and Goldmann applanation tonometer in children with ocular hypertension and related factors

Hou-Gang Li, Yan-Hui Chen, Fang Lin, Si-Yu Li, Qing-Hua Liu, Chun-Ge Yin, Xi-Yue Chen, Xin-Jie Zhang, Yue Qu, Yan-Nian Hui

This study accessed the agreement of intraocular pressure (IOP) values obtained from biomechanically corrected tonometer [Corvis ST (CST)], non-contact tonometer (NCT), and Goldmann applanation tonometer (GAT) in children with NCT measured-IOP (NCT-IOP) values of 22 mm Hg or more, and related factors. The accuracy of NCT in the diagnosis of pediatric ocular hypertension (OHT) is low. The agreement of CST-IOP and GAT-IOP was significantly higher in children with and without OHT than in those with NCT-IOP and GAT-IOP. Therefore, CST can be used as a good alternative for IOP measurement in children. The impacts of central corneal thickness (CCT) and axial length (AL) on NCT measurement need to be fully considered when managing childhood IOP.

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Corvis ST、非接触式眼压计、Goldmann压平眼压计在高眼压患儿眼压测量中的一致性及相关因素分析

该研究探讨了非接触式眼压计测量的儿童眼压在22 mm Hg以上时，生物力学校正眼压计 (Corvis ST)、非接触式眼压计和Goldmann压平眼压计所得眼压值的一致性及其相关因素。非接触式眼压计诊断小儿高眼压的准确性较低。无论是否存在高眼压，Corvis ST和Goldmann眼压计所得眼压值的一致性显著高于非接触式眼压计和Goldmann眼压计测量的一致性。因此，Corvis ST可作为儿童眼压测量的另一种选择。在处理儿童眼压时，应充分考虑角膜中央厚度和眼轴长度对非接触式眼压计测量的影响。

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    Bibliometric Research  

Bibliometric analysis of research relating to refractive cataract surgery over a 20-year period: from 2003 to 2022

Xiao-Yong Chen, Qian-Ru Wu, Min-Yue Xie, Di Zhang, Chun Zhang

This study aims at presenting a comprehensive analysis of the current status of refractive cataract surgery research in the past 20y (2003 to 2022) based on Web of Science data. According to the bibliometric analysis, the authors and institutions contribution, publication countries, journals, the sum of citations, and H-index, and the keywords of the latest hotspot were shown. Corneal astigmatism, cataract surgery method, postoperative visual-quality and postoperative complications relate researches has become the emerging hotspots, which can give a direction in the future researches.

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2003年至2022年屈光性白内障手术相关研究的文献计量分析

基于Web of Science数据库，该研究对过去20年（2003年至2022年）屈光性白内障手术研究的现状进行了全面分析，包括对相关作者和机构的贡献、出版国家、期刊、引文总数、H指数以及最新热点的关键词的文献计量分析。研究表明角膜散光、白内障手术方法、术后视觉质量和术后并发症的相关研究已成为新兴的热点，可为今后的研究提供方向。

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