AIM:To explore the relation of the prognosis and hemodynamics change in indirect optic nerve injury. METHODS:The PSV,EDV,TAMX and RI in central retinal artery,posterior ciliary artery and ophthalmic artery were measured with CDFI in 102 patients with indirect optic nerve injury,the relation of eyesight,bloodstream change and prognosis were observed.RESULTS:The PSV of posterior ciliary artery and ophthalmic artery of 95 patients in 102 patients were significantly higher(P<0.05),the EDV of them were significantly lower(P<0.05),the TAMX of them were lower(P<0.05) and the RI of them were clearly highter (P<0.01),The blood flow parameters of central retinal artery in 102 patients showed no significant difference (P>0.05). The lower eyesight was,the clearer bloodstream change was and the worse prognosis was.CONCLUSION:The patients with indirect optic nerve injury have the high speed and high obstruction blood-stream changes of posterior ciliary artery and ophthalmic artery. The clearer bloodstream change was,the worse prognosis was.