目的:探讨间接性视神经损伤患者眼血流动力学变化规律与预后的相关性。方法:应用彩色多普勒血流成像(CDFI)技术检测102例患者视网膜中央动脉、睫状后动脉、眼动脉收缩峰值速度(PSV)、舒张末期流速(EDV)、时间平均最大血流速度(TAMX)、阻力指数(RI),并对视力与血流改变、血流改变与预后的关系进行观察。结果:患者102例中,95例患者眼动脉、睫状后动脉PSV明显增加(P<0.05),EDV明显减低(P<0.05)、TAMX减低(P<0.05)、RI显著增高(P<0.01);102例患者视网膜中央动脉血流参数无显著差异(P>0.05)。视力越差,血流改变越明显,预后越差。结论:间接性视神经损伤患者眼动脉、睫状后动脉呈高速高阻血流动力学改变、血流改变越明显预后越差。

AIM:To explore the relation of the prognosis and hemodynamics change in indirect optic nerve injury. METHODS:The PSV,EDV,TAMX and RI in central retinal artery,posterior ciliary artery and ophthalmic artery were measured with CDFI in 102 patients with indirect optic nerve injury,the relation of eyesight,bloodstream change and prognosis were observed.RESULTS:The PSV of posterior ciliary artery and ophthalmic artery of 95 patients in 102 patients were significantly higher(P<0.05),the EDV of them were significantly lower(P<0.05),the TAMX of them were lower(P<0.05) and the RI of them were clearly highter (P<0.01),The blood flow parameters of central retinal artery in 102 patients showed no significant difference (P>0.05). The lower eyesight was,the clearer bloodstream change was and the worse prognosis was.CONCLUSION:The patients with indirect optic nerve injury have the high speed and high obstruction blood-stream changes of posterior ciliary artery and ophthalmic artery. The clearer bloodstream change was,the worse prognosis was.

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