目的:探讨盐酸环喷托酯滴眼液对屈光不正儿童验光睫状肌麻痹的效果。方法:对6～12岁屈光不正儿童60例120眼随机分为3组,分别用盐酸环喷托酯滴眼液、复方托吡卡胺滴眼液及阿托品眼膏滴眼。在用药前及用药后不同时间点对3组患者分别在电脑验光仪上进行客观验光并测量瞳孔直径,在综合验光仪上进行主观验光并用移近法测量调节力和剩余调节力。结果:盐酸环喷托酯滴眼液最大睫状肌麻痹时间是60min,在最大睫状肌麻痹状态下盐酸环喷托酯组剩余调节力较复方托吡卡胺组小(P<0.05),与阿托品组相近(P>0.05)。结论:用盐酸环喷托酯代替阿托品对6～12岁屈光不正非斜视儿童进行散瞳验光是可行的。

AIM:To investigate the effect of cyclopentolate hydrochloride on cycloplegia in children.METHODS:Sixty children (120 eyes) with refractive error ,aged from 6 to 12,were divided randomly into 3 groups:A,cyclopentolate hydrochloride eyedrop group;B,compound tropicamide group;C,10g/L atropine group. Before and after administration of these eyedrops,pupil size and objective refraction were checked on auto refractor,subjective refraction was checked in phoropter,and phoropter was used to check the accommodation response and residual accommodation respectively by "push-up"method. RESULTS:The time of maximum cycloplegia of cyclo-pentolate hydrochloride was 60 minutes. Under the ma-ximun cycloplegia,the residual accommodation in cyclopentolate hydrochloride eyedrop group and 10g/L atropine group had no significant difference. The residual accommodation in compound tropicamide eyedrop group was stronger than that of the other two goups (P<0.05).CONCLUSION:Cyclopentolate hydrochloride eyedrop is as effective as atropine for the measurement of refractive error in most healthy nonstrabismic children aged from 6 to 12.

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