AIM:To research characters of neurosensory retinal thickness in different macular sections of high myopia and analyze the correlation between neurosensory retinal thickness and gender, age, diopter as well as axial length.METHODS: One hundred and two patients with high myopia(102 eyes) were included.The neurosensory retinal thickness in different macular sections was measured by optical coherence tomography (OCT).The difference among neurosensory retinal thickness in every macular sections and the corelation between neurosensory retinal thickness and gender, age, diopter as well as axial length were analyzed.RESULTS:The minimum retinal thickness of fovea centralis was 175.34±29.01μm.OCT assessment revealed a significant difference of neurosensory retinal thickness in every macular sections.The inner regions were thicker than the outer regions, the nasal, superior and inferior side were thicker than the temporal side, the mean retinal thickness of central region and the minimum retinal thickness of fovea centralis was the thinnest. With the increase of the axial length, the mean retinal thickness of central region was increased while the superior side of the outer region was decreased.CONCLUSION:Perhapes the change of neurosensory retinal thickness in every macular sections caused by the increase of the axial length is the pathological basis before the macular degeneration of high myopia.