AIM:To compare the clinical effects of nucleus delivery between hydraulic pressure and lens loop method in manual small incision cataract surgery (MSICS).·METHODS:Totally 226 cases of cataract patients 253 eyes were randomly divided into hydraulic pressure nucleus delivery group and lens loop nucleus delivery group. The operating time,complications,corneal endothelial count and macular retinal thickness were observed preoperatively and postoperatively in both groups.·RESULTS:The average time of nucleus delivery:hydraulic pressure was 5±0.79s in nucleus delivery group and 4±1.23s in lens loop nucleus delivery group; complications in hydraulic pressure nucleus delivery group were less than those in lens loop nucleus delivery group. The corneal endothelial count before and after operation between the two groups was significantly different; the astigmatism after operation was not statistically different; the macular retinal thickness was not statistically different. ·CONCLUSION:Compared with the lens loop method,the hydraulic pressure nucleus delivery method is an effective,feasible,and economical approach with less complications for cataract surgery.