AIM:To probe into pathogenesis and factor,clinical symptom and physical sign,therapeutic method of the malignant glaucoma.METHODS:The clinical data of 20 cases of malignant glaucoma were analyzed retrospectively.RESULTS:Intraocular pressure recovered by drug control in 13 eyes,was effectively controlled by vitrectomy combined with intraoperative medication in 6 eyes,failed in 1 eye by drug treatment,which became blindness for refusing surgery.CONCLUSION:Fully understanding the pathogenesis and factor,clinical symptom and physical sign of the malignant glaucoma,making the rational healing solution,surgery combined with medication,can treat various malignant glaucoma effectively.