·Age-related macular degeneration(AMD)is the major reason for blindness of elder people in the world.Choroidal neovascularization(CNV)accounts for approximately 90% of severe vision loss caused by AMD.Verteporfin is the only photosensitiser in clinical application of photodynamic therapy(PDT)for treatment of AMD induced by CNV.This paper will give an overview on recent advances of combination therapy with verteporfin and antiangiogenic drugs for treatment of AMD induced by CNV,followed by investigating the difference efficacy of the treatment and the recovery of the eyesight.