·AIM:To observe the clinical effects of mitomycin C(MMC)on recurrent pterygium excision combined with corneal limbal stem cell transplantation.METHODS:The radical excision of recurrent pterygium was performed in 98 cases 98 eyes.The conjunctival flap with corneal limbal stem cell was transplanted into sclera and 0.2g/L MMC was used during operation.RESULTS:There was slight response after operation and the recurrence rate was 2%.CONCLUSION:The MMC applied in pterygium excision combined with corneal limbal stem cell transplantation is safe and effective.This method can rebuild the structure and function of corneal limbal,it has low recurrent rate and is worthy to be popularized.