AIM:To compare clinical outcomes on pseudophakic patients with AcrySof Toric and patients with AcrySof spherical intraocular lens(IOL).METHODS: A total of 56 age-related cataract patients (63 eyes) with corneal astigmatism more than 1.00 D were enrolled and divided into two groups. Experimental group: 27 cases (30 eyes), AcrySof Toric IOL was implanted after phacoemulsification. Control group: 29 cases (33 eyes), AcrySof Natural spherical IOL was implanted after phacoemulsification. A 6-month follow-up was planned. The uncorrected distance visual acuity (UCDVA), best-corrected distance visual acuity (BCDVA), preoperative and postoperative corneal astigmatism, postoperative refractive cylinder, toric IOL axis rotational stability were measured .RESULTS: The UCDVA at 1 week and 6 months postoperatively were significantly better in experimental group compared with control group (P<0.05). The mean refractive cylinder at 1 week and 6 months postoperatively were superior in experimental group, there were statistically differences between the two groups(P<0.05). The mean postoperative toric IOL rotation was 4.22±1.69 degrees, 4.64±1.97 degrees, 4.87±1.91 degrees, 5.39±1.56 degrees at 1 day, 1 week, 1 month, 6 months, respectively. There were no significant differences among the different months(P>0.05), the axis rotation was within 10 degrees in 96.67% of all eyes.CONCLUSION: Compared with AcrySof spherical IOL, AcrySof Toric IOL provides a safe, effective, stable method for correcting corneal astigmatism in cataract patients and show good rotational stability.