目的:比较弃瓣和常规机械法准分子激光角膜上皮瓣下磨镶术(epipolis laser in situkeratom ileusis,Epi-LASIK)手术矫正近视临床效果。方法:对38例72眼患者,低度近视行弃瓣(A组)和常规Epi-LASIK手术(B组)并随诊2a,比较两种手术方式早期临床反应,中、后期视力、haze、屈光度变化。结果:A,B两组手术均顺利;术后A组刺激症状轻于B组,差异有统计学意义;术后第2d:A组角膜透明眼数较B组多,差异有统计学意义;A,B两组术后7d;1mo视力比较差异有统计学意义,3,12,24mo比较差异无统计学意义;术后1moA,B两组屈光度比较差异有统计学意义,3,12,24mo比较差异无统计学意义;术后各时间两组haze差异无统计学意义。结论:Epi-LASIK、弃瓣Epi-LASIK在矫正中、低度近视安全、有效、稳定性好、可预测性好;弃瓣Epi-LASIK早期有效视力恢复方面、减轻术后不适感具有优越性。

AIM:To compare clinical results between epipolis laser in situ keratomileusis(Epi-LASIK) and epithelial removal Epi-LASIK for the treatment of low to moderate myopia.METHODS:This retrospective analysis comprised 38 eyes treated by Epi-LASIK(A group) and 34 eyes treated by epithelial removal Epi-LASIK(B group) on low to moderate myopia with a follow-up of 2 years. Recover situation of the early stage after operation,vision, haze,diopter of the middle,later stage were observed.RESULTS: All eyes were operated successfully. There was significant difference in the clinical symptom. The number of cornea transparent eyes in the second day of postopertaion of A group was more than B group. The difference had statistical signifcance. There was significant difference in the vision of 7 days,1 month of postoperation, that of A group was better than B group,and no significant difference in the 3 months,12 months,24 months of postoperation. There was significant difference in the diopter of 1 month postoperation of A group to B group,and no significant difference in the 3 months,12 months,24 months of postoperation. There was no significant difference in the haze of A group to B group.CONCLUSION: Both Epi-LASIK and epithelial removal Epi-LASIK have safety, effectiveness,stability and predictability.Epithelial removal Epi-LASIK is better in the valid vision and to alleviate discomfort in the early stage of postoperation than Epi-LASIK.

R779.63

中国江西省卫生厅基金项目(No.120080343)~~