单纯疱疹病毒性角膜炎(herpes simplex keratitis,HSK)是由病毒抗原引起的T淋巴细胞介导的迟发型变态反应。T淋巴细胞如何介导HSK免疫反应的详细机制目前仍不清楚,但从目前研究可总结:T淋巴细胞的细胞因子如IL-2,IL-10,IL-17,IFN-γ等促炎性因子在HSK的复发过程中起重要作用。本文将对T淋巴细胞及其细胞因子与HSK的研究进展做简要综述。

Herpes simplex keratitis (HSK) is a delayed allergy caused by viral antigens and T lymphocytes mediated.The detailed mechanism how T lymphocytes mediated HSK immune response is still unknown, but from the present research it can be summarized that the promote inflammatory factor of T lymphocyte cell factors such as IL-2, IL-10, IL-17,IFN-γ play an important role in the recurrence processing of herpes simplex keratitis. This paper will be briefly reviewed the progress about the research of T-lymphocytes and its cytokines with herpes simplex keratitis.

R772.22

中国国家中药管理局资助项目(No.06-07LP41);中国青海省科技厅资助项目(No.2007-N-129)~~