目的:观察配戴软性角膜接触镜对眼压测量的影响。方法:选取没有角膜病变的健康志愿者30例30眼(右眼)及无法以非接触眼压计测得眼压的患者21例21眼,角膜表面麻醉后,用非接触眼压计和Tono-pen眼压笔分别测量眼压,配戴角膜接触镜再次测量眼压,记录各次测得的平均眼压值。采用配对t检验比较配戴前后的眼压值及非接触眼压计与Tono-pen眼压笔所测得的眼压值的差异。结果:非接触式眼压计测量正常眼戴镜前后的眼压分别为:15.25±2.83mmHg和15.20±2.89mmHg(P=0.825);Tono-pen眼压笔测得戴镜前后的眼压值为15.93±2·43mmHg和16.60±3.09mmHg(P=0.146)。戴镜前后非接触眼压计与Tono-pen眼压笔所测得的眼压值没有统计学差异(P=0.052,0.096)。在21只无法以非接触眼压计测得眼压的患眼中,15眼戴镜后可测得眼压值,且所测得的眼压值与戴镜后Tono-pen所测得的眼压值没有明显差异(P=0·136)。患眼戴角膜接触镜前后Tono-pen眼压笔所测得的眼压值也没有明显的差异(P=0.266)。结论:配戴-0.50D软性角膜接触镜对正常眼及角膜病变眼眼压测量没有显著影响,提示有望以角膜接触镜作为媒介或载体实现眼压的测量和监控。

AIM:To evaluate the influence of soft contact lenses with -0.50D lens power on the measured value of the intraocular pressure (IOP) with the non-contact tonometer and Tono-pen tonometer.METHODS: Totally 30 healthy volunteers were included in this study. The right eyes were examined with slit-lamp microscope and there were no scars, edema, ulcers and other pathological changes in the corneas. IOP of the right eyes was measured after topical anesthesia with the non-contact tonometer and Tono-pen tonometer for each of them. After wearing a piece of soft contact lenses with -0.50D power, the IOP values were measured again, and then the IOP values were statistically evaluated. 21 eyes with corneal diseases or ocular hypertension whose IOP could not be measured by the non-contact tonometer were also included in this study. RESULTS: There was no statistical significance between naked eyes and eyes wearing soft contact lenses. The average IOP values measured with non-contact tonometer were 15.25±2.83mmHg in naked eyes and 15.20±2.89mmHg in eyes wearing soft contact lenses (P=0.825). The average IOP values measured with Tono-pen tonometer were 15.93±2.43mmHg in naked eyes and 16.60±3.09mmHg in eyes with soft contact lenses (P=0.146). Fifteen of the 21 eyes got IOP values by the non-contact tonometer after wearing soft contact lenses. The difference was not statistically significant between eyes with or without soft contact lenses.CONCLUSION: Soft contact lenses with -0.50D lens power has no influence on the measurement of IOP with non-contact tonometer and Tono-pen tonometer, indicating that relatively reasonable IOP may be gotten from corneas with scars and ulcers by wearing soft contact lenses. Moreover, it is possible that devices based on contact lens sensor may be used for IOP measurement in the future.

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中国武汉市科技计划基金资助项目(No.2008521-99600)~~