目的:探讨急性前葡萄膜炎的药物治疗方法,并观察其疗效和复发情况,为规范化前葡萄膜炎的药物治疗提供临床依据。方法:对48例急性前葡萄膜炎病例给予局部复方妥布霉素眼药水及复方托吡卡胺眼药水点眼,部分重症患者采用局部结膜下注射地塞米松3mg(0.6mL),1次/d,连用7d,对于伴有明确全身疾病病因者,加用口服激素冲击治疗3d,记录患者视力、眼压、前房反应、并发症情况,并随访1a,记录其复发情况。结果:所有病例于3d后症状体征缓解,1wk视力恢复,未发生眼局部严重并发症及全身并发症,6mo内无1例复发,1a内复发患者数为2例,复发率为4%。结论:绝大部分急性前葡萄膜炎单纯进行局部药物治疗,可获得良好的治疗效果,而全身激素治疗仅适用于有明确全身病病因患者且病变处于活动期。

AIM:To evaluate the drug treatment for acute anterior uveitis by observing its curative effect and recurrence. Also to provide clinical evidence for standardization of anterior uveitis drug treatment. METHODS: Forty-eight cases of acute anterior uveitis patients were involved in this study. All these patients were given compound tobramycin eyedrops and compound tropicamide eyedrops daily. For those severe cases, dexamethasone was given by subconjunctival injection, 3mg (0.6mL) daily for 7 days. Oral hormone was given for those cases related with explicit general diseases for 3 days. Visual acuity, intraocular pressure, anterior chamber reaction and complications were recorded. All cases were well followed up for 1 year and all recurrences were recorded. RESULTS: All cases were remitted after 3 days treatment both in symptoms and signs. Visual acuities were recovered after 1 week. No severe local or general complications were recorded yet. No recurrences were recorded within half an year, while only two recurrent cases were recorded within 1 year. The recurrence ratio was 4%.CONCLUSION: For most acute anterior uveitis patients, simply partial drug treatment showes good therapeutic effects. And oral hormone treatment is applieed only for cases with explicit general diseases.

R773.9