AIM:To evaluate the drug treatment for acute anterior uveitis by observing its curative effect and recurrence. Also to provide clinical evidence for standardization of anterior uveitis drug treatment. METHODS: Forty-eight cases of acute anterior uveitis patients were involved in this study. All these patients were given compound tobramycin eyedrops and compound tropicamide eyedrops daily. For those severe cases, dexamethasone was given by subconjunctival injection, 3mg (0.6mL) daily for 7 days. Oral hormone was given for those cases related with explicit general diseases for 3 days. Visual acuity, intraocular pressure, anterior chamber reaction and complications were recorded. All cases were well followed up for 1 year and all recurrences were recorded. RESULTS: All cases were remitted after 3 days treatment both in symptoms and signs. Visual acuities were recovered after 1 week. No severe local or general complications were recorded yet. No recurrences were recorded within half an year, while only two recurrent cases were recorded within 1 year. The recurrence ratio was 4%.CONCLUSION: For most acute anterior uveitis patients, simply partial drug treatment showes good therapeutic effects. And oral hormone treatment is applieed only for cases with explicit general diseases.