角膜厚度在角膜屈光手术术前检查中越来越受到眼科医师的重视。目前用于测量角膜厚度的仪器很多,大概分为两类:一类是基于超声波原理,有传统的超声测厚仪和超声生物显微镜;一类是基于光学原理,有Orbscan(Orbscan裂隙扫描角膜地形图/角膜测厚系统)、Pentacam(Pentacam眼前节综合分析系统)、OCT(optical coherence tomography,包括时域OCT,傅里叶域OCT)、角膜内皮镜及Lenstar等。各种检查方法都有其优点,也有其不足之处。但是,角膜厚度测量方法发展的趋势是简单易用,非接触性,重复性好,准确性好。本文旨在介绍角膜厚度的临床意义及测量方法新进展,并对各种测量方法进行分析总结,以供眼科医生在临床工作中参考。

Corneal thickness was more and more valued by ophthalmologists in the preoperative examination of corneal refractive surgery.Currently,there are many instruments used to measure corneal thickness,and most of them can be roughly divided into two categories.One is based on the principle of ultrasound,including the traditional ultrasonic corneal pachymetry and ultrasound biomicroscope(UBM),and the other is based on the optical principle,such as Orbscan,Pentacam,Optical Coherence Tomography(OCT,including time domain-OCT and fourier domain-OCT),corneal endothelium microscope,Lenstar and so on.Among these instruments above,each has its advantages and its disadvantages.However,the measurement of corneal thickness trends is in the development of noncontact,high repeatability and good accuracy.This paper describes the clinical significance of corneal thickness and the progress of the measurements,and all the measurement methods mentioned are analyzed and summarized for ophthalmologists in the clinical reference.

R779.6