AIM:To analyse the pathogeny of asthenopia.METHODS:The medical history of the outpatients with subjective sensation of asthenopia were asked.They were given particular examination to exclude systemic diseases and other eye diseases.The symptoms of asthenopia were recorded and analysed.RESULTS:The asthenopia included 10 symptoms.The causes included eye factors,systemic factors,environmental factors and comprehensive factors.CONCLUSION:Asthenopia shows many symptoms.The causes include many factors,the treatment should follow analysis of cause,then symptomatic treatment is given.