Conjunctival papilloma is a benign and epithelial tumour,it can be classified into conjunctiva type and limbus type depending on its site.Compared to the limbus type which is common in middle-aged people the conjunctiva type which usually occurs in children or adolesents is more common.The hyperplasia of conjunctival papilloma may leads to conjunctival squamous cell carcinoma.Conjunctival papilloma can be of viral origin(human papilloma virus,HPV),which is also related to conjunctival squamous cell carcinoma,so it is very important to detect HPV in patients for treatment and follow-up.The common treatment of conjunctival papilloma is sugical excision,but simple treatment is associated with high recurrence rate.Several types of therapy have been described,including liquid nitrogen cryotherapy,cauterization,cytotoxic drug and interferon.We report a case of recurrent limbus-based papilloma treated successfully with combined therapy.