AIM:To observe the effectiveness and safety of clear lens extraction and Acrysof ReSTOR multi-focal intraocular lens(IOL) implantation to correct high myopia in middle-and old-aged patients.METHODS:Phacoemulsification and implantation of Acrysof ReSTOR multi-focal IOL were performed on 44 eyes of 26 high myopic patients with clear crystalline lens.Preoperative and postoperative visual acuity,refractive error,corneal curvature,IOP,endothelial cell counting,stereoscopic vision,spectacles independent rate,vision habit,and satisfaction,of the patients were observed.RESULTS:No complications occurred intraoperatively.Postoperative uncorrected and best-corrected distant and near visual acuity,corneal curvature,and stereoscopic vision all improved than before surgery about 95.5% patients never wore spectacles,and 97.7% patients were satisfied with the refractive results.After operation,except for a transient increased intraocular pressure,no posterior capsular opacification,cystoid macular edema and retinal detachment were found during the follow-up period.CONCLUSION:Clear lens phacoemulsification and Acrysof ReSTOR multi-focal IOL implantation to correct high myopia in middle-and old-aged patients is a safe,effective procedure serving as a refractive surgery.Further follow-up over a longer period is needed to fully assess the effectiveness and complications of this operation.