目的：探讨干眼症患者泪液清除荧光素钠溶液的速率变化。 方法：选取干眼症患者30例，将20g/L荧光素钠溶液6μL一次滴入下结膜囊内，在裂隙灯下观察结膜囊内泪液中荧光素钠的消失时间，并与同期正常30人对照。 结果：本组干眼症患者泪液荧光素钠的清除时间右眼为2229.18±488.37s，左眼为2239.71±478.99s。正常人泪液荧光素钠的清除时间右眼为1173.35±161.79s，左眼为1188.92±200.32s。经Origin 6.0统计软件分析，两组间存在显著性差异(P＜0.01）。 结论：干眼症患者泪液清除荧光素钠的时限较正常人明显延长。干眼症患泪液清除时间的延长是干眼症发病机制中的一种补偿机制,对干眼症患者有益。

AIM:To explore the speed diversity of lacrimal fluid clearance of fluorescein sodium in dry eye patient. METHODS:Totally 30 cases of dry eye patient were chosen, 6μL of 20g/L Fluress was dropped in their conjunctival sac. The extinction time of fluorescein sodium in it was observed unde slit-lamp and compared with that in 30 cases of normal people. RESULTS:The extinction time of fluorescein sodium in right eye of dry eye patient was 2229.18±488.37s and that in left eye was 2239.71±478.99s. The extinction time of fluorescein sodium in right eye of normal people was 1173.35±161.79s and that in left eye of was 1188.92±200.32s. There was statistical significant difference between the two groups by analysis using Origin 6.0 statistics software(P＜0.01). CONCLUSION: The extinction time of fluorescein sodium in dry eye patient was prolonged than that in normal people. The extension is a compensation mechanism which can benefit patients.