AIM:To analyze the superiority of microscope strabismus surgery retrospectively. METHODS:Totally 387 cases with strabismus, male 224 cases, female 163 cases, aged 3 to 65 years, 296 cases were concomitant strabismus, 65 cases were paralytic strabismus, A-V syndrome in 19 cases, 7 cases of dissociated vertical deviation. All cases were performed strabismus surgery under microscope. The complex strabismus operation had anterior ciliary vessels separation and retention. RESULTS:All 23 cases were undercorrection, 8 cases overcorrection, strabismus correction rate reached 92.0%, and the efficaly rate reached 100%. No case of anterior segment ischemia occurred.The operation field was clear, operation accurate;post operative complications were minimal, local reactions mild, and recovery fast. CONCLUSION:Strabismus operation under microscope compared with the conventional naked eye strabismus operation, there are many advantages both in reducing operation trauma to improve operation accuracy and in reducing operation complication.