AIM:To explore the surgical skills of artificial nasolacrimal duct stent implantation, and to evaluate its effect. METHODS:From 2009 to 2011, 42 cases (42 eyes) with nasolacrimal duct obstruction were chosen to have the operation of permanent artificial nasolacrimal duct stent placement, which was through nasal cavity under local anesthesia. In the operation, original straight hole probe was replaced with side hole probe, to make the guide wire out automatically through adjusting the position of side hole. The clinical effect to each case was followed up for six months. RESULTS:The artificial nasolacrimal duct stent was successfully placed for 42 cases, the efficiency was one hundred percent based on six months follow-up after implanting surgery. CONCLUSION:The operation of artificial nasolacrimal duct stent implantation used for the treatment of chronic dacryocystitis and nasolacrimal duct obstruction is simple and safe, and its curative effect is sure, so this kind of operation is worth being popularized widely.