Abstract:AIM: To evaluate the changes of astigmatism induced by suture-fixation of foldable intraocular lens for aphakia correction. METHODS: Non-posterior capsular or disintegrated-posterior capsular eye were included in this study. Suture-fixation of foldable intraocular lens was performed on 20 cases (21 eyes). Keratometry measurements were obtained preoperatively, at postoperative 1 week, 1 month, 3 months respectively.The mean surgically induced astigmatism (SIA) and mean postoperative uncorrected visual acuity. Were recorded.SIAs were analyzed by "vector method". The changes of astigmatism were compared. RESULTS: The corneal refractive power between pre-operation and 1 week, 1 month, 3 months after surgery did not significantly change(P>0.05); the astigmatic power significantly changed(P<0.05) between pre-operation and 1 week after surgery, and did not significantly change (P>0.05) at 1 month and 3 months after surgery; the mean surgically induced astigmatism (SIA) power significantly changed(P<0.05) between 1 week and 1 month, 3 months after surgery, and did not significantly change (P>0.05) between 1 month and 3 months after surgery; astigmatic axis of large number of patients were ATR(against the rule) . CONCLUSION: The suture-fixation of foldable intraocular lens for aphakia correction affects corneal mean refractive power of optical zone minimally.The astigmatic power and axis are changed significantly at 1 month post-operation, and at 3 months are relatively stable.