AIM:To observe the effect of using rigid gas permeable contact lens (RGP) in visual impairment treatment of nystagmus and to investigate the significance. METHODS:Totally 11 cases(10 males, 1 female) were picked in outpatient who got nystagmus and astigmatism from March 2009 to September 2010.The cases were divided into two groups: group 1 wore RGP, group 2 were treated with traditional method. RESULTS:Group 1 got good effect and the effect of group was average. CONCLUSION:RGP has special effect on visual impairment treatment of nystagmus.