目的：观察生后3mo内行先天性白内障摘除术，并在眼轴发育至21mm时行二期人工晶状体植入术后6~8岁人工晶状体（IOL）眼患儿眼轴长度的变化。 方法：对15例26眼出生后3mo内行白内障摘除联合后囊膜连续环形撕囊及前段玻璃体切割术，并在眼轴发育至21mm（年龄在2周岁左右）时行二期人工晶状体植入术后的患儿进行连续观察。分别在6,7,8岁时测量术眼眼轴长度，另选取年龄和性别相匹配的正常儿童作为对照组，采用横断面病例对照研究比较两组间的差异。 结果：各年龄段术后患儿平均眼轴长度分别为23.75±140，23.88±1.73，23.91±1.55mm，与对应年龄对照组比较，6岁阶段眼轴发育比正常对照组儿童长，差异有统计学意义（P＜0.05)，7~8岁阶段与正常对照组无差异（P＞0.05）。 结论：出生后早期行先天性白内障摘除并在2周岁左右行二期人工晶状体植入术后的人工晶状体眼患儿，在6~8岁阶段，6岁时眼轴发育较同龄正常儿童快，但7~8岁时眼轴发育较同龄正常儿童基本相同。

To observe the axial length in early stage(6-8 years old) after pediatric cataract extraction and intraocular lens implantation. METHODS: A cross section case series of total 15 IOL infants (26 eyes), who had undergone pediatric cataract extraction, posterior continuous curvilinear capsulorhexis and anterior vitrectomy within 3 months and received intraocular lens implantation till the axial length of 21mm (about 2 years old). Patients were divided into 3 groups based on their ages at follow-ups:6 years group, 7 years group, 8 years group.The changes of axial lengths in each group were measured.The changes of axial length were analyzed and compared with those of normal age-gender-matched children. RESULTS:The mean axial length from 6-8 years group was 23.75±1.40,23.88±1.73 and 23.91±1.55mm respectively. Axial length in 6 years group was longer than that in normal control group , the difference was statistically significant (P<0.05), There was no difference between 7-8 years groups and normal control group (P>0.05). CONCLUSION: The axial length of young children,following second term IOL implantation at the age of 6 was longer than that of normal children,but there was little change compared with normal children after the age of 7.

辽宁省科学技术计划资助项目(No.2008408002-1）