AIM:To analyze clinical and histopathological features of eyelid basal cell carcinoma and improve the diagnostic level.  METHODS:Retrospective analysis of case series. Ninty-one cases (91 eyes) of basal cell carcinoma of eyelid of outpatients and inpatients dating from August 2001 to August 2011 were collected to review clinical and histopathological features. Parafin section and HE stain were applied to all cases. Immunohistochemical staining was further applied to some cases with diagnostic difficulties. RESULTS:Basal cell carcinoma of these cases occurred mostly in lower eyelid and inner canthus. The carcinoma was nodular and carcinoma cells appeared like basal cells. HE stain and immunohistochemistry were helpful fo diagnosis. CONCLUSION:Accurate diagnosis and timely treatment were not given to patients suffering from basal cell carcinoma of eyelid in the first diagnosis, which worsened their conditions. Basal cell carcinoma of eyelid should be differentiated from meibomian gland carcinoma, malignant melanoma, epidermoid carcinoma, etc