Abstract:AIM:To evaluate the efficacy, safety, and predictability of the implantation of Verisyse phakic iris-fixated intraocular lens(IOL) for the correction of severe myopia. METHODS:In this prospective study, 10 cases (13 eyes) with myopia at -15.00~-24.50 dioperts (D) were implanted with Verisyse phakic iris-fixated intraocular lens. Visual acuity, refraction, intraocular pressure, the Verisyse IOL position, contrast sensitivity, glare sensitivity, operative complications and poor visual symptoms were observed. RESULTS: The postoperative uncorrected visual acuity and best-corrected visual acuity(BCVA) significantly improved. The BCVA≥ 0.5 or better was presented in 100% eyes and ≥ 0.8 accounted for 85% at 3 months after surgery. There was no significant increase in mean intraocular pressure at each time point in one year after surgery. The Verisyse IOL appeared to be correctly positioned in the anterior chamber in all eyes. Contrast sensitivity and glare sensitivity in all eyes increased at 3 months postoperatively as compared with those of preoperative values (best spectacle corrected). Postoperative complications included as light inflammatory deposits on the PAC IOL surface at 3 months in 2 eyes; oval pupil in 1 eye. CONCLUSION:Verisyse IOL implantation for the correction of severe myopia is effective, safe and predictable. It can be a supplement for corneal refractive surgery, but follow up is still required for the evaluation of long term results.