AIM: To observe the therapeutic effect of phacoemulsification combined with vitrectomy for the treatment of high myopia complicated with cataract. METHODS: Vitrectomy combined with phacoemulsification were performed in 15 cases (18 eyes) with high myopia complicated cataract, postoperative visual acuity and complications were analyzed.RESULTS: During the postoperative follow-up, visual acuity was improved in all 18 eyes, and no related complications occurred. CONCLUSION: Phacoemulsification combined with vitrectomy decrease the risk of postoperative retinal detachment in the treatment of high myopia complicated with cataract.