AIM:To investigate the effects and safety of pilocarpine for the treatment of anterior chamber hyphema.METHODS:There were 87 cases(87 eyes) with grade I and II anterior chamber hyphema in our hospital, which were randomly divided into experimental group and control group. The control group was treated by conventional method. The experimental group used conventional treatment and pilocarpine in additon. Secondary hemorrhage rate and blood absorption time during treatment were observed and analyzed.RESULTS:The secondary hemorrhage rate was no difference in two groups, while the blood absorption time was obviously shorter in experimental group.CONCLUSION:Pilocarpine eye drops is a safe and effective drug. It can shorten the blood absorption time effectively when timely use 2 days after anterior chamber hyphema stop bleeding, the secondary hemorrhage rate was not increased during the treatment. It is worthy of popularizing in clinic.