目的:探讨LASIK术中单纯粗大水流复瓣与粗大水流联合吸血海绵复瓣的疗效。方法:收集2011-07/08就诊于我院行LASIK手术的211例418眼患者,按就诊先后顺序将患者随机分为2组,第一组105例208眼患者给予单纯粗大水流复瓣,第二组106例210眼患者给予粗大水流与吸血海绵联合复瓣,观察术后1d,1wk,1mo患者角膜瓣复位情况、最佳矫正视力及患者有无眩光不适等情况。结果:两组患者术后1d,1wk,1mo角膜均无明显错位及皱褶,术后第1d第一组3眼出现龟背纹,第二组2眼出现龟背纹,采用Fisher确切概率法,差异无统计学意义（P＞0.05）。两组患者术后1d视力分别为1.07±0.11,1.10±0.18,经独立样本t检验,差异无统计学意义（P＞0.05）。术后裸眼视力均达术前最佳矫正视力,且两组患者均未出现眩光等不适。结论:LASIK术中单纯粗大水流复瓣与粗大水流联合吸血海绵复瓣所达到的术后疗效等同。

AIM:To evaluate the effect of the treatment between gross stream irrigation and its combination with medical sponges used in corneal flap relocation during LASIK.METHODS:Totally 211 cases (418 eyes) from July 2011 to August 2011 in our hospital were collected. They were divided into 2 groups arranged by treatment order. The first group of 105 cases (208 eyes) used the gross stream irrigation to relocate the corneal flap while the second group of 106 cases (210 eyes) used the gross stream irrigation and medical sponges. The state of corneal flap, the best-corrected visual acuity (BCVA) and the patients'' feeling of glare were observed at the 1^st day, 1^st week and 1^st month after surgery.RESULTS:The two groups of patients were not observed any apparent replacement of corneal flap and ruffly corneal cap at the 1^st day, 1^st week and 1^st month after surgery. Three eyes in the first group were seen turtle pattern whereas two eyes were in the other group. We used Fisher''s exact probability and found there was no significant difference between the two groups (P＞0.05). The visual acuity of the two groups on the 2^nd day after surgery was 1.07±0.11 and 1.10±0.18 respectively. Univariate ttest indicated that there was no significant difference between the two groups. The postoperative uncorrected visual acuity (UCVA) is equal to the postoperative UCVA in both groups, and the patients feel well without glare.CONCLUSION:The postoperative effect of gross stream irrigation equals its combination with medical sponges used in corneal flap relocation during LASIK.