AIM:To investigate the clinical efficacy of Ahmed glaucoma valve implantation with mitomycin C(MMC)combined with retinal photocoagulation for treatment of neovascular glaucoma(NVG).

METHODS:The medical records of 41 cases 41 eyes of NVG who underwent Ahmed glaucoma valve implantation with MMC combined with retinal photocoagulation were retrospectively analyzed, including intraocular pressure(IOP), visual acuity, the operative success rate and surgery complications.

RESULTS:The average IOP postoperatively all had statistical difference compared with preoperative IOP(all P<0.05). The operative successful rate was 93%, in which 36 eyes(88%)with complete success, 2 eyes(5%)with success at certain condition and 3 eyes(7%)with failure. The difference of visual acuity was not significant(P>0.05). The complication after the operation included early hypotony in 4 eyes(10%), postoperative shallow anterior chamber in 1 eye(2%), hyphema in 3 eyes(7%)and tube occlusion in 1 eye(2%).

CONCLUSION:Ahmed glaucoma valve implantation with MMC combined with retinal photocoagulation is a safe and effective therapy to decrease the IOP of NVG.