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[摘要]
目的：评价并比较青光眼早期诊断仪GDxVCC、短波视野计(SWAP)、标准自动视野计(SAP)各参数诊断早期开角型青光眼的敏感性和特异性。
方法：采用GDxVCC和SWAP及SAP对正常人42例42眼和早期开角型青光眼患者84例84眼进行检查，绘制GDxVCC各参数(TSNIT，SA，IA，IES，NFI)ROC(receive operating characteristic curve)曲线，比较GDxVCC，SAP，SWAP的敏感性和特异性。
结果：TSNIT，SA，IA，IES，NFI的ROC面积分别为0.77，0.76，0.80，0.85，0.87。GDxVCC，SWAP，SAP的敏感性分别为80.6%，74.2%，67.8%； 特异性分别为95.2%，85.7%，76.2%。
结论： GDxVCC参数中，NFI和IES是区分正常人和青光眼最有效指标。GDxVCC诊断能力优于SWAP，SWAP优于SAP。
[Key word]
[Abstract]
AIM:To evaluate the sensitivity and specificity of GDxVCC, short wavelength automated perimetry(SWAP), standard automated perimetry(SAP)indices in the early diagnosis of open angle glaucoma.
METHODS: Forty-two normal subjects(42 eyes), 84 patients with open angle glaucoma(OAG, 84 eyes)were examined with GDxVCC, SWAP and SAP. Receiver's operating characteristic(ROC)curves of RNFL parameters were described and compared. The sensitivity and specificity of GDxVCC, SAP and SWAP on glaucoma diagnosis were calculated.
RESULTS: The area under ROC curve of GDxVCC parameters were: NFI(0.87), IES(0.85), IA(0.80), TSNIT(0.77), SA(0.76)respectively. The sensitivity of GDxVCC, SWAP, SAP were 80.6%, 74.2%, 67.8% respectively, and the specificity were 95.2%, 85.7%, 76.2% respectively.
CONCLUSION: NFI and IES are the best indices to distinguish normal subjects from patients with glaucoma. GDxVCC has the best diagnostic capability, SWAP is the second.
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