AIM: To explore the clinical feature of polypoidal choroidal vasculopathy(PCV)which would provide the basis for treatment and prognosis of PCV, according to the classification of indocyanine green angiography(ICGA)image, combined with fundus and optical coherence tomography(OCT)examination.

METHODS: Retrospective analysis of 33 PCV patients, who were diagnosed in Ningxia Eye Hospital with OCT, fundus fluorescein angiography(FFA)and ICGA. Comprehensive analysis the classification of PCV which were based on the ICGA image, and take the feature of PCV lesion into consideration.

RESULTS: Thirty-three PCV patients(54 eyes)were collected, 12 patients(36%)had monocular disease and 21 patients(64%)had binocular lesion. There were 20 male(61%)and 13 female(39%)included in the study. The age was raged from 42-86 years old and the average age was 70.63±9.42 years old. Forty-five eyes(83%)PCV lesion was located in macular area. Three types of PCV were classified according to ICGA image: polyps expansion type(20 eyes, 37%), abnormal branching vascular network type(16 eyes, 30%)and classical type(18 eyes, 33%). Twenty-seven eyes(50%)were suffered from pigment epithelial detachment(PED). The abnormal branching vascular network type(11 eyes, 68.8%)and classical type are(12 eyes, 66.7%)was more likely to suffer from PED. Twenty-three eyes(43%)have retinal neuroepithelium layer detachment including 10 eyes(62.5%)of abnormal branching vascular network type and 9 eyes(50.0%)of classical type. Thirty-one eyes(57%)shows active status 81.3% of abnormal branching vascular network type and 72% of classical type shows active status. Ten eyes(19%)appear fibrous membrane totally, including 7 eyes(43.8%)of branching vascular network type and 2 eyes(11.1%)of classical type. Thirty-seven eyes(69%)have nourishing vessels totally. Eighty-one percent of abnormal branching vascular network type and 94% of classical type have nourishing vessels.

CONCLUSION: The subtype of PCV such as branching vascular network type and classical type is apt to be active, the PED, retinal neuroepithelium layer detachment and nourishing vessels are more likely to appear in this two subtype rather than in the polyps expansion type, which always tend to be motionless. The branching vascular network type is easily to have fibrous membrane.