方法：选取40例50眼角膜炎患者，结合患者临床症状、体征，并行普通的裂隙灯显微镜检查及角膜激光共聚焦显微镜检查，均确诊为单纯疱疹病毒性角膜炎内皮型，将40例50眼患者随机分为两组，20例24眼采用单纯抗病毒治疗作为对照组，20例26眼采用抗病毒联合糖皮质激素治疗作为观察组，观察两组患者治疗效果。

结果：两组患者均顺利完成整个治疗计划，观察组患者在治疗期间未出现角膜溃疡扩大、加深，也无溃疡穿孔等并发症。观察组治疗有效18眼，总有效率为70%，对照组治疗有效12眼，总有效率为50%，两组差异具有统计学意义(P<0.05)。

结论：单纯疱疹病毒性角膜炎内皮型易与临床上多种眼病混淆，临床上应结合患者病史、临床症状及辅助检查确诊，可采用抗病毒治疗联合糖皮质激素治疗，提高治疗效果。

METHODS: Forty cases of keratitis patients were selected, and according to the clinical symptoms and signs, parallel ordinary slit-lamp microscope examination and corneal laser scanning confocal microscope examinations, they were diagnosed with corneal herpetic endotheliitis, and randomly divided into two groups, 20 patients with simple anti-viral treatment as control group, 20 were treated with anti-viral combination glucocorticoid treatment as the observation group, the treatment effects were observed.

RESULTS: All patients successfully completed the treatment, the observation group did not appear expanded corneal ulcer, perforated ulcer complications during treatment. The total effective rate in observation group and control group was 70% and 50%, respectively, the difference between the two groups was statistically significant(P<0.05).

CONCLUSION: The herpes simplex viruskeratitis endothelial can easily be mixed up with a variety of eye diseases, it should be read in conjunction with the patient's history, clinical symptoms and laboratory diagnosed clinical antiviral therapy combined with corticosteroid therapy can be used to improve the therapeutic effect.