难治性青光眼复合式小梁切除联合羊膜植入术疗效观察
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Clinical observation of bio-amnion implantation used in combined trabeculectomy for refractory glaucoma
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    摘要:

    目的:观察难治性青光眼复合式小梁切除联合羊膜植入术临床疗效。

    方法:选择我院80例86眼难治性青光眼患者,随机分为复合式小梁切除术联合羊膜植入术组(实验组)43眼和复合式小梁切除术组(对照组)43眼。观察术后眼压、滤过泡形成情况及并发症。

    结果:随诊12mo,平均眼压:实验组15.5±1.1mmHg,对照组19.7±2.5mmHg,两组术后平均眼压差异有统计学意义(P<0.05); 功能性滤过泡:实验组(86%)较对照组(67%)多,差异有统计学意义(P<0.05); 术后并发症(浅前房、脉络膜脱离和滤过泡渗漏)发生率实验组明显低于对照组。

    结论:复合式小梁切除联合羊膜植入术治疗青光眼具有手术成功率高,术后并发症发生率低的特点。

    Abstract:

    AIM: To observe the clinical effect of bio-amnion implantation used in combined trabeculectomy for refractory glaucoma

    METHODS: Totally 86 eyes of 80 glaucoma patients were randomly divided into 2 groups. In experimental group, 43 eyes underwent trabeculectomy combined with bio-amnion implantation. In control group, 43 eyes only underwent trabeculectomy combined. The intraocular pressure(IOP), filtrative bleb and complications were observed.

    RESULTS: Following-up for 12 months, IOP: there was significant difference between the average IOP(15.5±1.1mmHg)in experimental group and the average IOP(19.7±2.5mmHg)in control group(P<0.05). Filtrative bleb: the incidence of the functional filtering bleb(86%)in experimental group was more than the one in control group(67%), there was significant different between the two groups(P<0.05). The incidence of complications of post-operation(shallow anterior chamber, choroidal detachment and bleb leaking)was lower than the one of the control group obviously.

    CONCLUSION: Combined trabeculectomy with bio-amnion implantation can increase the rate of success and reduce the incidence of complications.

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薛馨槐,高阳.难治性青光眼复合式小梁切除联合羊膜植入术疗效观察.国际眼科杂志, 2013,13(5):944-946.

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  • 收稿日期:2013-01-14
  • 最后修改日期:2013-04-22
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  • 在线发布日期: 2013-05-06
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