方法：应用532nm激光对72例78眼视网膜裂孔进行激光光凝，按照裂孔所在不同象限、裂孔不同大小、以及裂孔是否伴有局限性视网膜脱离分组，进行统计学分析。

结果：裂孔位于视网膜上方象限者44眼，位于视网膜下方象限者31眼(视网膜上方和下方均发现裂孔者3眼，未纳入对照)，两组裂孔光凝效果比较，差异有统计学意义(P<0.05)； 裂孔直径≤2PD者37眼，裂孔直径>2PD者41眼，两组裂孔光凝效果比较，差异有统计学意义(P<0.05)； 不伴局部视网膜脱离的裂孔有45眼，伴有局部视网膜脱离的裂孔有33眼，两组裂孔光凝效果比较，差异有统计学意义。

结论：倍频532nm激光治疗视网膜裂孔安全有效，治疗上方视网膜裂孔、直径较小视网膜裂孔以及不伴局部视网膜脱离的裂孔效果更好。

METHODS: Seventy-two cases(78 eyes)with retinal holes were treated with 532nm frequency-doubled laser. All the eyes were divided according to the quadrants of location of retinal holes and the size of retinal hole and existence of local retinal detachment accompanying retinal holes. Statistical analysis was made on these data.

RESULTS: 1)The retinal holes were located in the upper quadrants of retina in 44 eyes and there were also retinal holes located in the lower quadrants of retina in 31 eyes(there were 3 eyes with retinal holes both located in the upper and lower quadrants of retina, which were not included in control group). The difference of photocoagulation effect between the two groups was statistically significant. 2)The retinal holes diameter ≤2 papilla diameter(PD)were present in 37 eyes, the holes diameter of retina >2PD were seen in 41 eyes, the difference of photocoagulation effect between the two groups was statistically significant. 3)Retinal holes without local retinal detachment were observed in 45 eyes, retinal holes with local retinal detachment were seen in 33 eyes, the difference of photocoagulation effect between the two groups was statistically significant.

CONCLUSION:Photocoagulation with 532nm frequency-doubled laser is effective and safe to treat retinal holes. The effect is better in patients with retinal holes in the upper quadrants and with the retinal holes diameter ≤2PD and without local retinal detachment.