AIM: To screen diabetic retinopathy(DR)in diabetes mellitus(DM)patients by non-mydriatic fundus photography, and to investigate the risk factors in DM patients for DR.

METHODS:A total of 768 patients with DM type 2 treated in the department of endocrinology in our hospital from November 2010 to December 2011 were enrolled in this study. All patients underwent non-mydriatic fundus photography, and were divided into two groups: non-diabetic retinopathy group(NDR group)and DR group, in accordance with the international clinical staging standard of DR released in 2002. Weight, height, blood pressure and medical history were recorded. Serum levels of fasting plasma glucose(FPG), lipids, glycated hemoglobin(HbA1c)and uric acid(UA)were measured.

RESULTS: Totally 317 out of 768 DM patients(41.3%)were diagnosed with DR. The detection rate in women was significantly higher than that in men(45.2% vs 37.6%, P<0.05). Compared with NDR group, DR group had older age, longer course and higher systolic blood pressure(SBP), FPG, Triglycerides(TG), HbA1c and UA level(P<0.05). Dinary logistic regression analysis showed that duration, gender, SBP and HbA1c were independent risk factors of DR in DM patients.

CONCLUSION:DR in DM patients is quite common and closely associated with duration, gender, blood pressure and glucose. Non-mydriatic fundus photography is a quite useful method for screening DR.