曲安奈德在玻璃体切割术中的临床应用
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Clinical application of triamcinolone acetonide on pars plana vitrectomy
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    摘要:

    目的:探讨玻璃体切割术(PPV)中应用曲安奈德(Triamcinolone Acetonide, TA)识别玻璃体后皮质(PVC)且辅助有效清除残余玻璃体后皮质的临床意义。

    方法:收集2009-03/2013-03行玻璃体切割术患者35例35眼,术中分次各注射TA 0.1mL。以帮助辨认玻璃体后皮质、视网膜前增殖膜、黄斑前膜,并有效清除。16例硅油填充,9例C2F6填充。术后随访6~12mo。

    结果:所有病例经玻璃体腔TA注射后,明显改善玻璃体后皮质、视网膜前膜、内界膜的辨认情况。其中,13例为玻璃体后皮质残留,19例为玻璃体后脱离(posterior detachment of vitreous,PVD)。经过有效的清除后,黄斑裂孔闭合率100%。视网膜复位率84.6%。

    结论:利用曲安奈德在玻璃体切割术中的良好可视性能有效识别玻璃体后皮质的残留、减少视网膜损伤、提高手术成功率。没有发现与TA有关的副作用。

    Abstract:

    AIM: To observe theclinical effect of using triamcinolone acetonide(TA)to recognize posterior vitreous cortex(PVC)and help effective residual vitreous posterior cortex on pars plana vitrectomy(PPV).

    METHODS: Thirty-five patients(35 eyes)underwent PPV with TA. An amount of 0.1mL TA solution was injected on the retinal surface to visualize and peel posterior vitreous cortex, epiretinal membranes(ERM)or internal limiting membrane(ILM)in these eyes. Among them, 16 cases were filled with silcon silicon oil and 9 cases were filled with C2F6. The follow-up time was for 6-12mo.

    RESULTS: In 35 cases,intraoperative staining with TA consistently improved direct visualization and delineation of the posterior hyaloids, ERM or ILM and facilitated their removal. Among them, vitreous posterior cortex left in 13 cases and PVD was found in 19 cases. Postoperatively, macular hole closure rate reached at 100%, and retina reposition rate was 84.6%.

    CONCLUSION: The good visibilityof TA formed during surgery is effective in recognizing residual vitreous posterior cortex, reducing the mechanical trauma to the retina, and improving operation success rate. And no serious complication related to TA was found in the study.

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杜红艳,钱志敏,王中颖,等.曲安奈德在玻璃体切割术中的临床应用.国际眼科杂志, 2014,14(2):363-364.

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  • 收稿日期:2013-10-12
  • 最后修改日期:2014-01-10
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  • 在线发布日期: 2014-01-20
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