AIM: To observe the efficacy of posterior neodymium:YAG(Nd:YAG)laser capsulotomy in patients with late capsular block syndrome(CBS)with posterior capsule opacification(PCO).

METHODS: The CBS 13 cases(18 eyes), which were identified as CBS with posterior capsule opacification, were treated with Nd:YAG laser capsulotomy. After changes of uncorrected distance visual acuity(UCDVA), intraocular pressure(IOP), aqueous humor, vitreous body and complications were observed after 1, 4, 24h; 1, 2wk postoperation.

RESULTS: Nd:YAG laser treatment of late CBS could improve patients' UCDVA. Some patients appeared anterior chamber particles, but did not cause inflammation. Some patients appeared a transient elevation of IOP after 1, 4, 24h, even needed treatment. But these changes were not statistically significant. All patients occurred the increase of vitreous opacities and floating shadow, but all recovered in 2wk.

CONCLUSION: Nd:YAG laser capsulotomy in patients with PCO associated with late CBS can increase visual acuity, but ophthalmologist should closely observe IOP and anterior chamber inflammation of patients, in order to provide prompt treatment.