对疑似高眼压症者视神经相关参数的分析研究
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Study of the relevant parameters of optic nerve of patients with suspected ocular hypertension
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    摘要:

    目的:研究正常者与疑似高眼压症者眼底视神经相关参数的差异性。

    方法:分别对疑似高眼压症组36眼,正常眼压对照组43眼的各部位视网膜神经纤维层厚度(pRNFL)、视盘相关参数、黄斑区神经节细胞复合体厚度(mGCCT)及视野指数进行测定,对其所测结果进行对比分析。

    结果:正常组与疑似高眼压症组的平均、上方及下方视网膜神经纤维层厚度,视盘相关参数(盘沿面积,视杯容积,平均杯盘比)相比均有显著性差异(P<0.01),黄斑区上方、下方及平均神经节细胞复合体厚度相比有显著性差异(P<0.01); 鼻侧视网膜神经纤维层厚度差异有统计学意义(P<0.05),颞侧视网膜神经纤维层厚度、视盘面积、平均变异(MD)和模式标准差(PSD)相比无显著性差异(P>0.05)。

    结论:疑似高眼压症者的平均、上、下方及鼻侧视网膜神经纤维层厚度,视盘相关参数(盘沿面积,视杯容积,平均杯盘比),黄斑区上方、下方及平均神经节细胞复合体厚度与正常人相比发生了改变。

    Abstract:

    AIM: To investigate the differences of the relevant parameters of optic nerve between patients with suspected ocular hypertension and normal people.

    METHODS: There were 36 eyes of suspected ocular hypertension and 43 normal eyes to test their retinal nerve fiber layer thickness(RNFL), the optic disk parameters, the thickness of macular ganglion cell complex(mGCCT)and visual field index. The analysis and comparison are made on the obtained results.

    RESULTS: There was significant difference(P<0.01)between the patients with suspected ocular hypertension and normal eyes in average, inferior and superior RNFL thickness, optic disk parameters(rim area, cup volume, average C/D ratio)and the average, inferior, superior thickness of macular ganglion cell complex(P<0.01). There was statistical difference between two groups in nasal RNFL thickness(P<0.05), but there was no statistical difference in temporal RNFL thickness, cup area, mean deviation(MD)and pattern standard deviation(PSD)(P>0.05).

    CONCLUSION: There is significant difference between normal and suspected ocular hypertension eyes in average, inferior and superior RNFL thickness, optic disk parameters(rim area, cup volume, average C/D ratio)and the average, inferior, superior thickness of mGCCT.

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要青清,刘丹.对疑似高眼压症者视神经相关参数的分析研究.国际眼科杂志, 2014,14(4):704-706.

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  • 收稿日期:2013-10-22
  • 最后修改日期:2014-03-18
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  • 在线发布日期: 2014-03-24
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