AIM: To observe the therapy effect of standard prescription on ametrop amblyopia in hyperopic children.

METHODS: This study included 270 cases(54 eyes)with complete data, and followed up 24mo. All the amblyopic children were given standard prescription and were divided into progressive addition glass group, under corrected group and full corrected group. And all were observed for their therapy effect and the average healing time in low hyperopic, moderate hyperopic and high hyperopic children with ametropic amblyopia respectively.

RESULTS: In low hyperopic children, the difference of the therapy effect of the three corrected methods were insignificant in two years. The meam cure time of the three corrected methods were(7.33±2.11)mo in progressive addition glass group;(9.0±3.71)mo in under corrected grope;(12.5±5.17)mo in full corrected group. Three groups of independent samples by paired t-test showed: the difference between progressive addition glass group and under corrected grope(t=1.66, P>0.05)was statistically insignificant; the difference between progressive addition glass group and full corrected grope(t=3.92, P<0.01)was statistically significant; the difference between under corrected grope and full corrected grope(t=2.33, P<0.05)was statistically significant. In moderate hyperopic chileren, the differences of the therapy effect of the three corrected methods were significant in two years(χ²=6.75; P<0.05). The difference between progressive addition glass group and under corrected grope(χ²=6.3; P<0.01)was statistically significant; the difference between progressive addition glass group and full corrected grope(χ²=8.1; P<0.005)was statistically significant. The mean cure time of the three corrected methods were(14.0±4.87)mo in progressive addition glass group;(16.93±4.58)mo in under corrected grope;(17.93±4.42)mo in full corrected group. Three groups of independent samples by paired t-test showed: the difference between progressive addition glass group and under corrected grope(t=2.88, P<0.01)was statistically significant; the difference between progressive addition glass group and full corrected grope(t=3.9, P<0.01)was statistically significant; the difference between under corrected grope and full corrected grope(t=1.01, P>0.05)was statistically insignificant. In high hyperopic amblyopic children, the difference of the therapy effect and the healing time of the three corrected methods were insignificant in two years.(χ²=2.43, P>0.05. t=1.49, P>0.05; t=1.46,P>0.05; t=1.11, P>0.05).

CONCLUSION: Under standard prescription, application of progressive multifocal glasses provides a new effective treatment for ametropic amblyopia in hyperopic children, and makes up the deficiency of the whole straightening and under correction in clinical treatment.