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[摘要]
老年黄斑变性(age-related macular degeneration，AMD)是西方国家白种人不可逆性视力下降的首要原因。目前，AMD的治疗方法主要有抗血管内皮生长因子抗体(Anti-vascular endothelial growth factor，Anti-VEGF)的药物治疗、光动力学疗法(photodynamic therapy，PDT)、局部应用曲安奈德(triamcinolone acetonide，TA)及激光治疗(纳秒激光等)等。本文通过对比分析老年黄斑变性的不同治疗方法的作用原理、治疗效果、副作用、经济成本，为临床治疗提供依据。
[Key word]
[Abstract]
Age-related macular degeneration(AMD)is the leading cause of irreversible visual loss in elderly people among white-dominated population. At percent, treatment for AMD includes anti-vascular endothelial growth factor antibody(Anti-VEGF)drug treatment, photodynamic therapy(PDT), topical application of triamcinolone acetonide(TA)and laser therapy(nanosecond laser)etc. Through comparative analysis of different treatment methods of AMD, we review the mechanism, clinical efficacy, adverse events and cost effectiveness to provide the basis for clinical treatment.
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