AIM: To discuss the feasibility of using the visual quality analyzer KR-1W to guide the relatively personalized aspheric intraocular lens(IOL)implants to make the whole eye spherical aberration close to 0.1μm.

METHODS: In this prospective case series study, the corneal spherical aberration with 6mm aperture of 73 patients(100 eyes)was measured with KR-1W Visual Function Analyzer 1d before surgery. For the sake of the whole postoperative spherical aberration were close to 0.1μm, 9 cases(16 eyes)with corneal spherical aberration <0.15μm were implanted Sofport Advanced Optic IOL, named AO group; 45 cases(57 eyes)with corneal spherical aberration 0.25～0.3μm were implanted AcrySof IQ IOL, named IQ group; 19 cases(27 eyes)with corneal spherical aberration >0.35μm were implanted Tecnis ZA9003 IOL, named Tecnis group. Aspherical IOL was implanted after phacoemulsification through a cornea 2.75mm incision without suture.Uncorrected visual acuity, beat corrected visual acuity, spherical aberration of the whole eye and jnternal optics(mainly IOL)at 6mm pupil diameter were examined at 3mo postoperatively. The relevant data were analyzed using t-test and variance analysis.

RESULTS: The whole ocular spherical aberration at 6mm pupil diameter in all postoperative were 0.084±0.032μm; in Tecnis group, the data were 0.091 ± 0.021μm; in AO group, the data were 0.0814-0.013μm; IQ group were 0.093±0.042μm. There was no significantly different between the predicted value and actual value of ocular spherical aberration at 6 mm pupil diameter in all postoperative(t=1.932, P=0.061)and in the three groups. The difference value in the predicted values of the preoperative spherical aberrations of the whole eye and the actual values after surgery was 0.013±0.041μm; there was no statistically significant difference(F=2.537, P=0.091). Respectively compared the uncorrected visual acuity and besta corrected visual acuity among three groups of postoperative, no significant difference were found(F=0.897, P=0.421; F=1.423, P=0.097).

CONCLUSION: Personality selection of aspheric IOL based on preoperative corneal spherical aberration of patients is feasible and produces satisfactory target postoperative total spherical aberration.