AIM: To analyze the differences of postoperative visual quality among LASIK guided by wavefront aberration, aspheric cutting and conventional cutting.

METHODS: From our hospital between January 2007 and December 2009, the independent line during LASIK surgery in 90 patients(180 eyes)with myopia as the research subjects. According to the different way of cutting and the voluntary principle of nonrandom selection, the patients were divided into three groups: aspheric cutting group, wavefront guided cutting group and conventional cutting group. Each group included low myopia(diopter: ≤-3.00D), moderate myopia(diopter: -3.25～-6.00D), high myopia(diopter: -6.25～-9.00D)and 10 cases(20 eyes). Postoperative uncorrected visual acuity, corneal Q value, higher-order aberrations(RMS value)and visual quality parameters, such as patients with visual satisfaction were compared and analyzed among three groups.

RESULTS: Postoperative uncorrected visual acuity was 1.0 or more after surgery with three different laser cutting modes, without significant difference between groups(P=0.26). Postoperative corneal Q value increased, it was smaller in aspheric cutting group than other two groups, with a statistically significant difference(P<0.05). The high-order aberration RMS values of three groups was increased compared with preoperative, it was significantly smaller in aspheric cutting group and wavefront guided cutting group than that in conventional cutting group(P<0.05). There was no significant difference between aspheric cutting group and wavefront guided cutting group(P>0.05). All patients were satisfied after surgery, it was was obviously higher in aspheric cutting group than other two groups, with no statistical significance(P=0.57)

CONCLUSION:Conventional, aspheric and wavefront guided cutting in LASIK for the treatment of myopia are able to obtain a better visual quality and clinical application, while the effect of aspheric cutting is better.