方法：本研究为回顾性病例研究。对POAG 44例66眼进行5a的随访，其基线和5a随访时的所拍摄的眼底照片用于视盘形态学的评估。本研究对前后视盘旁萎缩弧β(β区)的变化和青光眼进展进行判断，并且用计算机软件测量了POAG患者基线和随访时盘沿/视盘面积比、β区/视盘面积比、垂直杯盘比。

结果：基线时66眼POAG眼有48眼存在β区，其中β区扩大20眼(42%)。β区扩大组和无变化组之间基线的年龄，屈光，性别，垂直杯盘比，盘沿/视盘面积比，β区/视盘面积比之间无统计学差异。排除屈光度数大于-3.00D的眼后，19例无进展青光眼中β区扩大4例(21%)，25例进展青光眼中β区扩大15例(60%)，两者之间有显著统计学差异(χ²=6.67，P=0.011)。

结论：POAG中有β区扩大组青光眼进展率大于无扩大组，β区的变化可能对POAG病情的进展有预测作用。

METHODS: In this retrospective study, 66 eyes of 44 POAG subjects were selceted and made the morphology evaluation of the color fundus photographs(30°)which were taken in baseline and five-year visit. The change of peripapillary atrophy β zone(β zone)and the progress of optic disc damage was detected. The disc rim/disc area ratio, β zone/disc area ratio and vertical cup/disc ratio both baseline was calculated by computer software.

RESULTS:Forty-eighty eyes had β zone in 66 POAG subjects in baseline, β zone of 20 eyes(42%)was expanded, there was no significant difference on age, refractive error, gender, vertical cup/disc ratio, rim/disc area ratio, β zone/disc area ratio of baseline between β zone-developed group and β zone-undeveloped group. After excluded the eyes' refractive error >-3.00D, β zone of 15 eyes(60%)had developed in 25 progressed glaucoma eyes and 4 eyes(21%)had undeveloped in 19 unprogressed glaucoma eyes. There was significantly different(χ²=6.67, P=0.011).

CONCLUSION: The prevalence of β zone development in progressed group is larger than unprogressed group in POAG. To monitor the change of β zone may have some effects in predicting the progress of POAG.