方法：分析2007-01/2013-12于我院行玻璃体切除联合硅油填充术后出现黄斑下积液6mo的患者31例31眼，根据手术方式分为A、B组，A组行硅油取出术，B组行硅油取出联合内界膜剥除、C₃F₈填充术，手术后随访时间为6～12(平均为8.33±1.45)mo，对比分析术后3、6mo两组的LogMAR最佳矫正视力提高率、黄斑平均神经上皮层厚度。

结果：术后3mo比较各组平均LogMAR 最佳矫正视力(best-corrected visual acuity，BCVA)均较术前有提高，差异有统计学意义(t=2.326、2.577，P<0.05)，A组和B组LogMAR BCVA提高率比较，差异有统计学意义(χ²=5.473，P<0.05)； 术后6mo比较各组平均LogMAR BCVA均较术前有提高，差异有统计学意义(t=4.216、3.801，P<0.05)，A组和B组LogMAR BCVA提高率比较，差异有统计学意义(χ²=4.210，P<0.05)。术后各组黄斑平均神经上皮层厚度变薄。

结论：硅油取出联合视网膜内界膜剥除、C₃F₈填充术是治疗硅油填充眼持续性黄斑下积液的有效方法。

METHODS: Thirty-one patients(31 eyes)with persistent submacular fluid after pars plana vitrectomy combined with silicone oil filled in our hospital from January 2007 to December 2013. According to operation mode, those patients were divided into group A(silicone oil removal)and group B(ILM peeling combined silicone oil removal and C₃F₈ filled).Follow-up time after surgery was 6～12(mean 8.33±1.45)mo. The LogMAR best-corrected visual acuity(BCVA)and the neuroepithelial thickness of macular fovea was observed at postoperative 3, 6mo.

RESULTS: Postoperative 3mo LogMAR BCVA was improved in each group compared to preoperative LogMAR BCVA, the difference was significant(t=2.326, 2.577, P<0.05). the difference on LogMAR BCVA improvement rate of group A and B had statistical significance(χ²=5.473, P<0.05). Postoperative 6mo LogMAR BCVA was improved in each group compared to preoperative LogMAR BCVA, the difference was significant(t=4.216, 3.801; P<0.05). The difference on LogMAR BCVA improvement rate of group A and B had significance(χ²=4.210, P<0.05). Postoperative the neuroepithelial thickness of macular fovea was decreased in each group compared to that of preoperative

CONCLUSION: ILM peeling combined silicone oil removal and C₃F₈ filled is an effective method in treatment of silicone oil-filled eye with persistent submacular fluid.