AIM: To study the related factors of comprehensive treatment effect on anisometropic amblyopia children, and to provide a theoretical basis for clinical intervention.

METHODS: Totally 100 cases of anisometropic amblyopia children in our hospital from October 2013 to October 2014 were selected and were divided into groups A, B and C according to curative effect after 6～18mo's treatment. Fifty-four cases of group A were judged to be cured, 34 cases of group B were judged to be improved, and 12 cases of group C was invalid. The age, compliance, anisometropia degree, anisometropia type, amblyopia degree and fixation behavior were analyzed.

RESULTS: Anisometropia type among the three groups of patients showed no significant difference(P>0.05). While the age, compliance, anisometropia degree, amblyopia degree and fixation behavior among three groups of patients had statistically significant differences(P<0.05). By regression equation analysis, the influence level of various factors on comprehensive treatment effect was in sequence of amblyopia degree, anisometropia degree, fixation behavior, age, compliance.

CONCLUSION: There are closed relationship between comprehensive treatment effect and age, compliance, anisometropia degree, amblyopia degree, fixation behavior, but there is no significant correlation between anisometropia type and comprehensive treatment effect.