[关键词]
[摘要]
纳米材料在眼部给药方面的应用主要集中在纳米控释系统，由于纳米材料的特有属性，使用纳米材料运载治疗眼部疾病的药物与传统给药方式相比具有很大的优越性，主要表现在药物的纳米制剂具有更高的生物利用率和更低的副作用。因此纳米控释系统在眼科具有良好的应用前景。目前，已经有多种不同类型的纳米控释系统被用于提高眼部给药效率的研究，包括纳米胶束、纳米颗粒、纳米混悬剂、脂质体和树突状分子等。本文就纳米控释系统在眼科给药方面应用的研究进展作一综述。
[Key word]
[Abstract]
The ophthalmic application of nanometer materials are mainly concentrated on controlled releasing systems. Due to the unique properties of nanometer materials,it has great advantages in carrying ophthalmic drugs compared with the conventional method, mainly in higher bioavailability and fewer side effects. As a result, nano-controlled releasing system has good application prospect in ophthalmology. At present, a variety of different types of nano-controlled releasing systems have been used to enhance the efficiency of the ophthalmic drugs, including nanomicelle, nanoparticles, nanosuspensions, liposomes,dendrimers, etc. In this paper, the research progress as well as the application of nano-controlled releasing system on ophthalmologic administration is reviewed.
[中图分类号]
[基金项目]
吉林省卫生厅青年基金(No.2013Q005); 吉林省科技厅国际合作项目(No.20130413025GH)
