方法：选择2012-12/2013-12在我院行全激光TransPRK手术的高度近视患者68例136眼，随访1a，观察眼部刺激症状、视力、眼压、haze和屈光度等情况进行分析。

结果：术后无不适感54例108眼，14例28眼患者出现眼干涩、磨疼、异物感。两组患者术后3、6mo，1a裸眼视力比较差异均有统计学意义(t=2.04，P=0.047)。术后3mo时裸眼视力最佳，术后6mo视力稳定。术后1a裸眼视力均达到0.8以上，与术前最佳矫正视力比较无明显下降。haze发病率低，多数在0～1级。通过对夜间视力、干眼、视疲劳等进行调查问答。满意度达85%。

结论：TransPRK术因术中全激光，术后反应轻、视力恢复快、干眼、haze发病率低，在治疗高度近视方面，其安全性高，疗效满意，是治疗高度近视较为理想的表层手术方式之一。

METHODS:One hundred and thirty six eyes in 68 patients with high myopic were treated using Amaris trans-epithelial PRK during December 2012～December 2013. Post-operative pain, haze, visual acuity, refraction and intraocular pressure(IOP)were analyzed during 12mo follow-up post-operatively.

RESULTS:One hundred and eight eyes in 54 patients felt no discomfort at all, while 28 eyes in 14 patients reported dry eye, slight pain and foreign body sensation. UCVA between the two groups showed statistically different at 3, 6mo and 1a(t=2.04, P=0.047). UCVA at 3mo was the best compared with those at other time pionts, and became stable at 6mo. UCVA of all patients were above 0.8 at 12mo,and had no difference with that before operations(t=1.508, P=0.1670). Haze were hardly seen, and most of them were between grade 0～1. The patients' satisfaction was over 85% according to the survey about night vision, dry eye and asthenopia.

CONCLUSION:Because of the great advantages of no-touch, fast recovery and less side effects, trans-epithelial PRK has great efficiency, safety and satisfaction. It now is the most ideal method of surface ablation for high myopia treatments.