[关键词]
[摘要]
目的:分析普拉洛芬和玻璃酸钠滴眼液结合中药治疗老年糖尿病超乳术后干眼伴有角膜上皮损伤的临床疗效。
方法:随机选择2013-03/2014-09我院眼科老年糖尿病超声乳化术后并发干眼症的患者82例108眼为研究对象,按照随机数字法分为试验组45例58眼,对照组37例50眼。对照组予以普拉洛芬滴眼液、玻璃酸钠滴眼液滴眼; 试验组在对照组的基础上予以芪明颗粒口服; 分别于治疗前、后检测两组患者泪液分泌试验(Schimer 试验)、泪膜破裂时间(break-up time,BUT)及角膜上皮荧光素染色(Fluorescein,FL)。
结果:试验组治疗后Schimer值、BUT(10.17±3.12mm、16.21±4.29s)均显著高于治疗前(4.91±0.69mm、7.74±2.01s),P<0.05; 治疗后试验组患者Schimer值、BUT(10.17±3.12mm、16.21±4.29s)显著高于对照组(9.01±2.87mm、16.21±4.29s),P<0.05; 试验组治愈率55.2%显著高于对照组34.0%,试验组总有效率100%显著高于对照组96.0%,P<0.05。
结论:普拉洛芬、玻璃酸钠滴眼液联合中药芪明颗粒治疗老年糖尿病超声乳化术后干眼症及角膜上皮损伤患者具有良好的临床疗效。
[Key word]
[Abstract]
AIM:To discuss the effects of pranoprofen and sodium hyaluronate eye drops combined with traditional Chinese medicines in the treatments on elderly patients with diabetics and dry eyes, injuring of corneal epithelial after phacoemulsification.
METHODS:Randomly selected 82 elderly patients(108 eyes)with diabetics who were dry eyes and injuring of corneal epithelial after phacoemulsification in our hospital from March 2013 to September 2014. According to the random number methods, 82 cases were divided into experimental group with 45 cases(58 eyes)and control group with 37 cases(50 eyes). The cases in control group were treated with pranoprofen and sodium hyaluronate eye drops, besides those in experimental group were treated with grains of Qi Ming. All cases were respectively detected with Schimer test, Break-up time(BUT), Fluorescein(FL)before and after the treatments.
RESULTS:The Schimer value, BUT(10.17+3.12mm,16.21+4.29s)after the treatments were significantly higher than those(4.91+0.69mm,7.74+2.01s)before the treatments for the cases in experimental group(P<0.05). After the treatments, the Schimer value, BUT(10.17+3.12mm,16.21+4.29s)of the cases in experimental group were significantly higher than those in control group(9.01+2.87mm,16.21+4.29s)(P<0.05). The cure rate of experimental group(55.2%)was significantly higher than that of control group(34.0%), and the total effective rate(100%)of the experimental group was significantly higher than that(96.0%)of the control group(P<0.05).
CONCLUSION:The effects of pranoprofen and sodium hyaluronate eye drops combined with traditional Chinese medicines on elderly patients with diabetics and dry eyes, injuring of corneal epithelial after phacoemulsification are very good.
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