Abstract:AIM:To investigate the effect of onset time(T)for macula choroidal thickness(CT)in myopia patient.
METHODS:A prospective cohort study was designed.One hundred and twenty-two myopia patients(244 eyes; 67 male and 55 female; aged 30～41 years, mean 35.1±4.6 years old)who received preoperative examinations from March 2014 to April 2015 were recruited in this study. The patients were divided into three groups according to onset time(T):group A(T≤5a), group B(5aF=1.56,P>0.05),age(F=2.13,P>0.05),best corrected visual acuity(BCVA, F=1.41,P>0.05),corneal curvature(F=1.65,P>0.05)and axial length(F=1.89,P>0.05)among the three groups. The choroid in macular region was measured by enhanced depth imaging(EDI)using spectral-domain optical coherence tomography(SD-OCT). This study recorded the CT at subfoveal(SFCT), 1mm at temporal(T1mm), nasal(N1mm), superior(S1mm)and inferior(I1mm)to the fovea and 3mm temporal(T3mm), nasal(N3mm), superior(S3mm)and inferior(I3mm)to the fovea, respectively. The differences of CT at the same position among the three groups were analyzed.RESULTS:The mean SFCT for group A,B,C were 238.32±57.95μm, 230.58±67.21μm, 221.63±62.37μm respectively in this study. The CT was found no significant difference in different locations except N3mm(tA-B=4.34,P<0.05)between group A and B. The CT was found no significant difference in different locations except N3mm(tB-C=7.61,P<0.05)between group B and C. The CT was found significant difference in different locations, except T3mm(t=0.76,P>0.05)between group A and C. Significant difference was found at N3mm(tA-B=4.31,t B-C=7.59,tA-C=12.18; P<0.05)among the three groups.
CONCLUSION:The choroidal thickness decreases as the myopia onset time is earlier, especially at nasal.
