AIM: To explore the main risk factors related to the incidence of endophthalmitis in patients after cataract surgery in China and to provide evidence for prevention.

METHODS: The results of 5 studies on the main risk factors of endophthalmitis in patients after cataract surgery were analyzed by Meta-analysis method.

RESULTS: The pooled odds ratio values and 95% CI of age(≥70), diabetes, vitreous overflow, operative time(≥10min), common operating room and control of using time of topical anesthetic were 1.81(95% CI: 1.43-1.69),3.66(95% CI: 1.64-8.16),2.21(95% CI: 1.46-3.32),3.54(95% CI: 2.47-5.06),2.77(95% CI: 2.07-3.72),2.09(95% CI: 1.53-2.86).

CONCLUSION: The main risk factors of endophthalmitis were the age(≥70), diabetes, vitreous overflow, operative time(≥10min), common operating room and control of using time of topical anesthetic.